Uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids: 2 years' outcome from the randomized EMMY trial.

نویسندگان

  • Nicole A Volkers
  • Wouter J K Hehenkamp
  • Erwin Birnie
  • Willem M Ankum
  • Jim A Reekers
چکیده

OBJECTIVE The purpose of this study was to compare the 2 years' efficiency of uterine artery embolization (UAE) with hysterectomy in the treatment of menorrhagia caused by uterine fibroids in a randomized controlled trial. STUDY DESIGN Twenty-eight Dutch hospitals recruited patients with uterine fibroids and menorrhagia, who were eligible for hysterectomy. Patients were randomized to UAE or hysterectomy. The primary endpoint was if UAE could avoid a subsequent hysterectomy in at least 75% of cases. Secondary endpoints were changes in pain, bulk-related complaints, and uterine and dominant fibroid volume reduction. RESULTS One hundred seventy-seven patients were randomized to UAE (n = 88) or hysterectomy (n = 89). Two years after treatment 23.5% of UAE patients had undergone a hysterectomy. There were no significant differences in improvement compared to baseline in pain and bulk-related complaints. Uterine and dominant fibroid volume reduction in UAE patients was 48.2% and 60.5%, respectively. CONCLUSION UAE is a valuable alternative treatment for symptomatic uterine fibroids. Nevertheless, when patients seek for certainty on the cessation of bleeding problems, a hysterectomy remains the treatment of choice.

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I-43: Uterine Artery Embolization(UAE),An Alternative Treatment for Fibroids

Background: To evaluate the results (rates of success, complications and clinical outcomes), advantages or disadvantages of Uterine Artery Embolization (UAE). Materials and Methods: We were able to follow 28 women with uterine fibroids, ranging age of 21 to 48 years (mean age 34 y), who underwent UAE in Mostafa Khomeini Hospital from May 2005 to June 2014, for the period of 6 months to 8 years....

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عنوان ژورنال:
  • American journal of obstetrics and gynecology

دوره 196 6  شماره 

صفحات  -

تاریخ انتشار 2007