Uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids: 2 years' outcome from the randomized EMMY trial.
نویسندگان
چکیده
OBJECTIVE The purpose of this study was to compare the 2 years' efficiency of uterine artery embolization (UAE) with hysterectomy in the treatment of menorrhagia caused by uterine fibroids in a randomized controlled trial. STUDY DESIGN Twenty-eight Dutch hospitals recruited patients with uterine fibroids and menorrhagia, who were eligible for hysterectomy. Patients were randomized to UAE or hysterectomy. The primary endpoint was if UAE could avoid a subsequent hysterectomy in at least 75% of cases. Secondary endpoints were changes in pain, bulk-related complaints, and uterine and dominant fibroid volume reduction. RESULTS One hundred seventy-seven patients were randomized to UAE (n = 88) or hysterectomy (n = 89). Two years after treatment 23.5% of UAE patients had undergone a hysterectomy. There were no significant differences in improvement compared to baseline in pain and bulk-related complaints. Uterine and dominant fibroid volume reduction in UAE patients was 48.2% and 60.5%, respectively. CONCLUSION UAE is a valuable alternative treatment for symptomatic uterine fibroids. Nevertheless, when patients seek for certainty on the cessation of bleeding problems, a hysterectomy remains the treatment of choice.
منابع مشابه
GENERAL OBSTETRICS AND GYNECOLOGY: GYNECOLOGY Uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids (EMMY trial): Peri- and postprocedural results from a randomized controlled trial
متن کامل
I-43: Uterine Artery Embolization(UAE),An Alternative Treatment for Fibroids
Background: To evaluate the results (rates of success, complications and clinical outcomes), advantages or disadvantages of Uterine Artery Embolization (UAE). Materials and Methods: We were able to follow 28 women with uterine fibroids, ranging age of 21 to 48 years (mean age 34 y), who underwent UAE in Mostafa Khomeini Hospital from May 2005 to June 2014, for the period of 6 months to 8 years....
متن کاملUterine artery embolization vs hysterectomy in the treatment of symptomatic uterine fibroids: 10-year outcomes from the randomized EMMY trial.
BACKGROUND Since 1995 uterine artery embolization has been described as an alternative for hysterectomy in patients with symptomatic fibroids. Many studies including several randomized controlled trials established uterine artery embolization as a valuable treatment. These randomized controlled trials reported outcomes in terms of health-related quality of life, clinical outcomes, efficacy, and...
متن کاملI-47: Uterine Artery Embolization for Symptomatic Uterine Fibroids: a Prospective Study on 102 Patients in Iran
Uterine fibroids are benign tumors occurring in 20-50% of women in their reproductive age. They are the most Abstracts of the 12th Royan International Congress on Reproductive Biomedicine frequent indication for hysterectomy at Pre-menopausal age. Fifty percent of fibroids are asymptomatic and require no treatment, but the rest may cause menorrhagia, dysmenorrhoea, dyspareunia, abdominal disten...
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Uterine fibroids are benign solid tumors that are present in the majority of women. While often asymptomatic, fibroids can result in abnormal uterine bleeding, pelvic pressure, pain, subfertility, dyspareunia and other symptoms. Submucous and intramural fibroids are most associated with heavy menstrual bleeding; subserosal fibroids are more often innocuous unless sufficiently large so as to con...
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ورودعنوان ژورنال:
- American journal of obstetrics and gynecology
دوره 196 6 شماره
صفحات -
تاریخ انتشار 2007